Tissue Plasminogen Activator -7351C/T Polymorphism and Lacunar Stroke * Response:
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منابع مشابه
Tissue plasminogen activator -7351C/T polymorphism and lacunar stroke.
Tissue Plasminogen Activator 7351C/T Polymorphism and Lacunar Stroke To the Editor: Jannes et al1 reported that a polymorphism in the tissue plasminogen activator (tPA) gene ( 7351C/T) was associated with ischemic stroke in an Australian population. Stratification for stroke subtype demonstrated an association with lacunar infarction (OR: 2.7; 95% CI, 1.1 to 6.7), but not with other stroke subt...
متن کاملTissue Plasminogen Activator 7351C/T Polymorphism and Lacunar Stroke
Tissue Plasminogen Activator 7351C/T Polymorphism and Lacunar Stroke To the Editor: Jannes et al1 reported that a polymorphism in the tissue plasminogen activator (tPA) gene ( 7351C/T) was associated with ischemic stroke in an Australian population. Stratification for stroke subtype demonstrated an association with lacunar infarction (OR: 2.7; 95% CI, 1.1 to 6.7), but not with other stroke subt...
متن کاملTissue plasminogen activator -7351C/T enhancer polymorphism is a risk factor for lacunar stroke.
BACKGROUND AND PURPOSE Occlusive thrombosis is an important component of small- and large-vessel ischemic stroke. Endogenous tissue plasminogen activator (TPA) is the primary mediator of intravascular fibrinolysis and is predominantly expressed by the endothelium of small vessels. The acute release of TPA is influenced by the TPA -7351C/T polymorphism and therefore may play an important role in...
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Background: Thrombolytic therapy is the recommended treatment of acute ischemic stroke. It is crucial to evaluate the treatment results with recombinant Tissue Plasminogen Activator (r-TPA) in patients with acute stroke. Objectives: This study aimed to evaluate treatment outcomes with r-TPA in patients with acute stroke in a referral stroke center in Iran. Materials & Methods: In this retrosp...
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Background: Hypercoagulability and hypofibrinolysis are among the symptoms exhibited by diabetic patients. Our study aimed to address the polymorphic nature of Alu DNA fragment in the human tissue plasminogen activator gene within diabetes mellitus (DM) Jordanian patients. Methods: Genomic DNA was isolated from 76 DM patients and 60 non-diabetic Jordanian individuals, and the Alu fragment was a...
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ژورنال
عنوان ژورنال: Stroke
سال: 2005
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.0000199663.64894.4f